Module I:
Endocrine & Cardiometabolic
Join the leaders in advanced anti-aging medicine
Unlock the power of hormonal and metabolic balance to optimize health, enhance performance, and extend lifespan. This foundational module provides an in-depth exploration of key endocrine and cardiometabolic systems, equipping healthcare professionals with actionable strategies to drive lasting patient wellness.
Transform Patient Outcomes with an Integrated Approach
From cortisol regulation to blood sugar management, this module examines the intricate connections between hormonal health, metabolic function, and cardiovascular wellness. Learn to identify imbalances, implement evidence-based interventions, and coach patients for success—because longevity starts with a strong foundation.
Key Topics Covered
Hormonal Balance & Optimization
- The essential role of key hormones in health and disease
- Strategies for restoring and maintaining hormonal equilibrium
Cortisol & Stress Regulation
- The impact of chronic stress on metabolism and longevity
- Techniques to optimize cortisol levels and support resilience
Thyroid Function & Metabolic Health
- Understanding thyroid hormone synthesis and its role in performance
- Best practices for diagnosing and managing thyroid disorders
Blood Sugar & Insulin Mastery
- The science of glucose metabolism and insulin resistance
- Lifestyle and nutritional interventions for long-term metabolic health
Cardiovascular Health & Longevity
- The intricate relationship between endocrine health and heart function
- Risk assessment, prevention, and integrative treatment strategies
The Bigger Picture: Sleep, Bone Health & Mental Well-Being
- How sleep apnea, bone loss, mood disorders, and depression link to endocrine and metabolic dysfunction
What You'll Gain from This Module
- A deeper understanding of hormonal and cardiometabolic interactions
- Evidence-based tools to manage cortisol, thyroid, and metabolic disorders
- Patient-centered coaching techniques to drive real, sustainable results
- Strategies to integrate longevity-focused care into your medical practice
About the Fellowship in Longevity Medicine
This module is part of the Fellowship in Longevity Medicine, a cutting-edge program designed for medical professionals seeking to master precision medicine, longevity science, and peak healthspan optimization.
- Apply the latest research in endocrine and cardiometabolic health
- Develop personalized treatment plans based on cutting-edge science
- Help patients achieve lifelong vitality through integrative strategies
Start your journey today—empower your patients to thrive!
Faculty
Schedule
Welcome & course Overview
- Introduction to the interconnected nature of endocrine and cardiometabolic health
- Overview of key learning objectives and case-based approach
HRT: Clinical Benefits & Risks?
- Assess current evidence regarding patient outcomes, including cardiovascular, bone, brain, and breast health, when using bioidentical and synthetic hormones.
- Compare the safety profiles, efficacy, and potential side effects of bioidentical versus synthetic hormone therapies.
Sleep Disorders as an Underlying Pillar of Metabolic Disruption
- Describe how sleep deprivation and disorders such as insomnia, sleep apnea, and circadian rhythm disturbances contribute to metabolic dysfunction.
- Implement behavioral and lifestyle modifications, including sleep hygiene practices, stress management, and circadian rhythm alignment, to improve sleep quality.
Hormone Testing – The Scientific Evidence (Non-CME)
- Discuss the various clinical studies and discuss the pros and cons of each testing modality.
- Review the DUTCH test and how to interpret
Hormonal Balance: The Foundation of Health
- Identify key hormones such as insulin, cortisol, thyroid hormones, sex hormones, and growth hormone, and describe their primary functions.
- Evaluate the impact of hormonal dysregulation on metabolic conditions such as diabetes, obesity, and cardiovascular disease.
Cortisol Regulation & HPA Dysfunction: All Dots Connected
- Explain the role of the HPA axis in the body’s stress response, including cortisol’s effects on metabolism, inflammation, and immune function.
- Implement evidence-based interventions, including lifestyle modifications, adaptogenic herbs, and stress management techniques, to restore cortisol balance.
Thyroid Disorders – A Metabolic Approach
- Describe the feedback loop involving the hypothalamus, pituitary gland, and thyroid (HPT axis) and its impact on metabolic homeostasis.
- Use case studies to illustrate diagnostic challenges, including interpreting TSH, free T3, free T4, and thyroid antibodies.
The Journey from Hormone Disruption to Cardiometabolic Consequences
- Explain how dysregulation of key hormones (insulin, cortisol, thyroid hormones, and sex hormones) disrupts glucose metabolism, lipid profiles, and blood pressure regulation.
- Recognize early clinical signs of hormone disruption, including weight gain, fatigue, hypertension, and impaired glucose tolerance.
Q&A Panel
Sahar Swidan, PharmD; Mark Houston, MD, MS, MSc | 0.5 hr
Sahar Swidan, PharmD; Mark Houston, MD, MS, MSc | 0.5 hr
Morning Coaching: How to Talk to Patients About Hormones & Cardiometabolic Risk
Mark Houston, MD, MS, MSc | 0.5 hr
Mark Houston, MD, MS, MSc | 0.5 hr
Vascular Biology & Cardiovascular Disease for the Clinician
- Explain the effects of key hormones such as estrogen, progesterone, testosterone, cortisol, and thyroid hormones on vascular health, blood pressure regulation, and endothelial function.
- How metabolic dysfunction accelerates vascular aging
- Explain the role of chronic inflammation and oxidative stress in vascular aging, contributing to arterial stiffness, hypertension, and impaired blood flow.
Insulin Resistance & Diabetes: The New Epidemic
- Analyze the molecular mechanisms driving insulin resistance, including chronic inflammation, mitochondrial dysfunction, and lipotoxicity.
- Integrate pharmacological treatments, supplements and lifestyle modifications, tailoring interventions to each patient’s needs for sustainable diabetes reversal.
Pathophysiology & Clinical Management of Hypertension
- Describe the effects of cortisol, insulin, sex hormones and thyroid hormone imbalances on vascular tone, fluid balance, and sympathetic nervous system activity.
- Implement evidence-based interventions to restore metabolic function, reduce vascular inflammation, and slow the progression of vascular aging, improving long-term cardiovascular outcomes.
Nutrition & Cardiometabolic Syndrome
- Identify the effects of key nutrients, including saturated fats, trans fats, omega-3 fatty acids, fiber, and antioxidants, on heart health.
- Review the various diets and the risks and benefits of each diet.
Pathophysiology & Clinical Management of Hypertension Continued
Case-Based Discussion: Hypertension, Dyslipidemia & Cardiovascular Risk Reduction
Mark Houston, MD, MS, MSc | 2.5 hr
Case-Based Discussion: Hypertension, Dyslipidemia & Cardiovascular Risk Reduction
Mark Houston, MD, MS, MSc | 2.5 hr
Morning Coaching: How to Implement Hormonal & Cardiometabolic Strategies in Clinical Practice
Mark Houston, MD, MS, MSc | 0.5 hr
Mark Houston, MD, MS, MSc | 0.5 hr
Endocrine Disruptors & Detoxification Strategies
- Explain how EDCs interfere with hormone synthesis, signaling, and metabolism contributing to conditions such as infertility, metabolic dysfunction, and thyroid disorders.
- Outline evidence-based detoxification protocols that support the liver’s Phase I and Phase II detoxification pathways to eliminate EDCs.
Testing Strategies for Endocrine Disorders
- Combine hormone testing with clinical assessments and lifestyle factors to develop Comprehensive treatment protocols.
- Monitor patient progress through follow-up testing, adjusting interventions as needed to optimize endocrine function and long-term health outcomes.
Male Hormones: The Latest Clinical and Dosing Guidelines
- Describe the impact of low testosterone (hypogonadism) on metabolic health, including increased fat mass, insulin resistance, and cardiovascular risk.
- Integrate personalized treatment plans that consider the patient’s age, health status, and long-term health goals to optimize men’s health throughout aging.
Prescription Writing & HRT Protocols for Women
- Discuss various HRT preparations and dosing guidance and review some recommendations for monitoring and adjusting therapy.
- Discuss various dosage forms and conversion guidelines for HRT.
Breakout Session – Female Patient Cases & Panel Discussion
Tara Scott, MD; Sahar Swidan, PharmD | 1 hr
Tara Scott, MD; Sahar Swidan, PharmD | 1 hr
Breakout Session – Male Patient Cases & Panel Discussion
Myles Spar, MD; Sahar Swidan, PharmD | 1 hr
Myles Spar, MD; Sahar Swidan, PharmD | 1 hr
Q&A Panel Discussion
Tara Scott, MD; Myles Spar, MD; Sahar Swidan, PharmD | 0.5 hr
Tara Scott, MD; Myles Spar, MD; Sahar Swidan, PharmD | 0.5 hr