Module III - 2026

Join the Leaders in
Advanced Anti-Aging Medicine

With emerging research highlighting the impact of environmental factors, such as toxins like mold, on brain health and aging, this course provides actionable strategies to support your patients' overall health from a holistic perspective. You will gain the tools to understand how environmental exposures influence longevity, brain health, and detoxification, as well as the role cardiovascular care plays in improving long-term wellness.

Key Focus Areas

In this module, you will explore the intricate links between longevity, environmental health, detoxification, and brain health, including the following critical areas:

Longevity Science

Grasp the biology of aging and lifespan extension, exploring the genetic and epigenetic factors that influence longevity.

Learn how to incorporate lifestyle interventions to promote a longer and healthier life.

Environmental Health

Gain insight into the harmful effects of environmental toxins, such as mold and pollutants, on physical and cognitive health.

Learn strategies to reduce exposure to environmental risks and understand the importance of clean air, water, and food for overall health.

Detoxification

Explore the body's natural detoxification pathways and how to support them.

Discover nutritional and lifestyle strategies for effective detoxification, and how vital organs like the liver, kidneys, and skin contribute to the detoxification process.

Cardiovascular and Brain Health

Examine the interconnectedness of heart health and cognitive function.

Learn prevention and management strategies for cardiovascular disease, with an emphasis on integrative approaches to maintaining brain health throughout life.

Cognitive Health and Aging

Explore the effects of aging on the brain and the strategies available to mitigate cognitive decline.

Learn about the impact of environmental toxins, traumatic brain injury (TBI), and chronic pain on brain health, and gain insights into therapies to prevent neurodegenerative diseases.

Interconnected Systems

Understand how environmental factors, detoxification, and cardiovascular health interact to impact brain health and longevity.

Learn to integrate these systems into a comprehensive, patient-centered approach to longevity and well-being.

What You’ll Gain from this Module

Understand the science of aging, cognitive decline, and strategies for promoting longevity.
Identify the health impacts of environmental toxins, particularly on brain health.
Implement effective detoxification methods to support cognitive function and general health maintenance.
Apply cardiovascular health knowledge to maintain brain function and overall longevity.
Develop a holistic, integrative approach to preventing cognitive decline and optimizing brain health throughout the lifespan.

About the Fellowship in Longevity Medicine

This module is part of the prestigious Fellowship in Longevity Medicine, an advanced program designed for healthcare professionals who aim to master precision medicine, longevity science, and healthspan optimization.

By completing this module, you will:

Gain a Comprehensive Understanding of Environmental Health: Learn how environmental toxins impact both physical and cognitive health and develop strategies to mitigate exposure.
Master Practical Detoxification Methods: Discover effective detoxification techniques and their role in supporting overall health and longevity.
Apply Integrative Approaches to Cardiovascular and Cognitive Health: Understand the interconnection between cardiovascular health and cognitive function and adopt integrative strategies for maintaining and optimizing both.

Learn More

Start your journey today-empower your patients to thrive!

Faculty

Erin Amato,
MD

David Benavides,
MD

Matthew Bennett,
MD

Sanjay Bhojraj,
MD

Gordon Crozier,
DO

David Haase,
MD

James LaValle,
RPh, CCN, MT, DHM, DHPh, B.S.Pharm

Allison Remy,
PA-C

Todd LePine,
MD

Kenneth Sharlin,
MD

Elizabeth Stuller,
MD

Sahar Swidan,
PharmD

Schedule

7:30 am

Setting Up Your Brain and Weekend for Success! (Non-CME)

Frame how brain health, sleep, autonomic tone, and vascular status influence learning, decision making, and longevity practice.
Introduce weekend themes: brain optimization, pain, environment, detox, and neurophenotyping.
Offer a simple “brain priming” routine attendees can experience and later adapt clinically.

Sahar Swidan, PharmD, BCPS, ABAAHP

8:00 am

Brain Optimization and Neuronal Health: What is Robbing our Brain Function

Explain a systems biology approach to brain optimization, emphasizing the gutbrain axis, neuroendocrine signaling, and metabolic health in maintaining cognition
Evaluate how microbiome disruption, glycemic dysregulation, and inflammation drive neurodegeneration, mental fatigue, and mood shifts, with integrative strategies for prevention and repair
Analyze dopamine/reward circuitry in overeating, behavioral addictions, and sugar dysregulation, with practical ways to recalibrate reward pathways

Todd LePine, MD

10:00 am

Break

10:30 am

Measuring the Brain You’re Treating: qEEG, ERP, HRV & Functional Neurometrics

Differentiate qEEG, ERP, HRV, and related neurometrics: what each measures, strengths, and limitations.
Show sample reports and translate findings into treatment decisions (sleep, autonomic balance, neuroinflammation, attention issues).
Clarify when to add neurometrics vs. relying on standard cognitive and mood screening tools, and when to refer.

David Haase, MD

12:00 pm

Lunch Sponsored by KBMO (Non-CME)

1:30 pm

From Cognitive Decline to Dementia: Integrative Strategies for Brain Health

Apply evidence based functional interventions (nutraceuticals, diet, detox, neuroprotective protocols) that support neuronal repair and cognitive resilience.
Build stepwise workups and longitudinal algorithms for cognitive decline for functional/integrative based longevity clinics (screening tools, labs, imaging, and referral thresholds).

Kenneth Sharlin, MD

3:30 pm

Break

4:00 pm

Neurovascular Longevity: Linking Brain Health, Endothelium & Cardiovascular Care

Explain how endothelial dysfunction, arterial stiffness, and microvascular disease drive cognitive decline, depression, and “brain fog,” connecting Module I–II cardiometabolic content with brain outcomes.
Review practical cardiovascular markers and tests with direct brain relevance (BP patterns, lipids, ApoB/Lp(a), CAC, carotid IMT, HRV, NO biology, simple vascular imaging) and how to interpret them through a neurovascular lens.
Present stepwise neurovascular optimization protocols: blood pressure and lipid targets, lifestyle and exercise prescriptions, nitric oxide and endothelial support, and when to refer to cardiology for more advanced evaluation.

Sanjay Bhojraj, MD

5:00 pm

Therapeutic Apheresis, Immune Reset & Brain Longevity

Introduce therapeutic apheresis and immune reset strategies as advanced tools for inflammatory and auto-immunemediated neurodegeneration.
Identify clinical scenarios where FP/IM clinicians should consider these approaches and how to evaluate, counsel, and refer.
Outline co-management strategies and realistic expectations for outcomes, emphasizing their place within broader neurovascular and brain longevity plans

David Haase, MD

6:00 pm

Close of Session

7:30 am

Back Pain and Generalized Body Pain Syndromes- What is the Connection

Differentiate mechanical, inflammatory, neuropathic, and centralized pain presentations.
Identify red flags for urgent imaging/referral versus integrative management.
Build tiered protocols combining movement, manual therapies, meds, supplements, sleep and stress work, and when needed neuromodulation/intervention.

Matthew Bennett, MD

9:00 am

Migraines and Other Headaches-Innovations in Treatment

Differentiate the pathophysiological mechanisms underlying migraines, tension-type headaches, and cluster headaches, including the roles of neuroinflammation, vascular changes, and neurotransmitter imbalances.
Evaluate emerging and evidence-based treatment innovations—including CGRP inhibitors, neuromodulation devices, and functional medicine approaches—for both acute and preventive headache management.
Develop personalized, multimodal treatment strategies that integrate pharmacologic, nutritional, hormonal, and lifestyle interventions to improve outcomes in patients with chronic or refractory headaches.

Sahar Swidan, PharmD, BCPS, ABAAHP

10:00 am

Break

10:30 am

The Glymphatic System, Sleep Architecture & Brain Detoxification

Describe glymphatic physiology and sleep stages in amyloid and metabolite clearance.
Identify sleep disruptors and their impact on cognitive and cardiovascular risk.
Outline integrative sleep/glymphatic optimization strategies.

David Benavides, MD

12:00 pm

Lunch

1:00 pm

Environmental Medicine Essentials: What’s Making Your Patients Sick?

Identify environmental and structural factors (mold, VOCs, EMFs, ventilation) linked to chronic illness and cognitive decline.
Explain mechanisms by which exposures disrupt immune, neurological, endocrine, and vascular function.
Provide a practical environmental history and testing framework plus first line treatment strategies.

Allison Remy, PA-C

3:00 pm

Break

3:30 pm

Exposome and Detoxification Protocols for Longevity

Define the exposome and its impact on cellular and mitochondrial health.
Identify biomarkers and tests for toxic burden and detox capacity.
Design safe, personalized detox protocols with clear monitoring and follow up.

James LaValle, RPh, CCN

5:00 pm

Close of Session

8:00 am

A Fresh Look into Brain Anatomy & Neurotransmitter Physiology as it relates to Depression, Anxiety, ADD with treatment protocols

Review key brain regions and circuits implicated in mood, attention, and social function.
Explain neurotransmitter interplay in depression, anxiety, and ADD.
Apply functional protocols and discuss integration with standard psych meds.

Elizabeth Stuller, MD

10:00 am

Break

10:30 am

Endocannabinoid System/Ketamine/Oxytocin/LDN Modulation in Neurological Disorders

Describe ECS, oxytocin signaling, and NMDA modulation in pain, mood, and neuroinflammation.
Evaluate clinical applications, indications, and safety for LDN, ketamine, and oxytocin.
Clarify regulatory status and practical implementation/referral models.

Sahar Swidan, PharmD, BCPS, ABAAHP

12:00 pm

Lunch

1:00 pm

Psychedelics and Ketamine in Mental Health and Longevity: Where Are We Now?

Provide a concise overview of current evidence and regulatory status for ketamine and classic psychedelic assisted therapies in treatment resistant depression, PTSD, substance use disorders, and existential distress, with emphasis on durability of benefit and implications for healthspan.
Differentiate ketamine from classic psychedelics in terms of mechanism, clinical indications, delivery models (IV ketamine infusions, intranasal esketamine, clinic based psychedelic assisted psychotherapy), and safety/monitoring requirements relevant to primary care and longevity practices.
Identify appropriate patient profiles, key screening and contraindications, and practical collaboration pathways between longevity/primary care clinicians and specialty ketamine/psychedelic centers, including how to structure preparation and integration to stabilize gains in mood, cognition, and resilience.

Erin Amato, MD

2:30 pm

NeuroPhenotyping Framework: Classifying & Treating the Complex Brain
Phenotyping Framework: Classifying & Treating the Complex Brain

Present phenotype categories (inflammatory, neuroendocrine, toxicant, trauma, metabolic).
Map phenotypes to patterns, core tests, and first line treatment priorities.
Show how to adapt the phenotype as patients respond over time.

Gordon Crozier, DO

3:30 pm

Break

4:00 pm

Designing a Brain-First Longevity Clinic Visit

Outline templates for new “brain longevity” visits and follow-ups, incorporating neurovascular, environmental, sleep, and mood considerations.
Demonstrate integration of neurometrics, exposome, detox, and neurophenotypes into 3–12 month care plans.
Address documentation, coding, and pacing of advanced therapies.

Gordon Crozier, DO; James LaValle, RPh, CCN

5:00 pm

Module Summary and Q&A (Non-CME)