Low Dose Naltrexone (LDN) has been traditionally used in pain modulation, but its effects are now known to be wide reaching and its use has been adopted in a variety of disease states. LDN has been demonstrated to modulate the immune system and numerous inflammatory markers; which has expanded its use in a variety of conditions such as autoimmune diseases, neuropsychiatric disorders, dermatological conditions and more.

Through an actionable learning format, this one day workshop will examine these valuable uses of Low Dose Naltrexone (LDN) in daily clinical practice.


  • Discuss the history and mechanism of action of LDN
  • Integrate how opiate receptor modulation will lead to optimal effect
  • Synthesize the role of immune modulation in cancer treatment
  • Define neuroinflammation and ways to modulate
  • Apply the use of LDN in various dermatological skin disorders


  • What is low dose naltrexone (LDN), how does it work, history, pharmacology, mechanism of actions, and the role in inflammatory bowel diseaseLeonard Weinstock, MD

  • The Gut Connection to Disease: SIBO, MCASLeonard Weinstock, MD

  • Opiate Receptor Modulation: Best Approach to Optimal EffectPaul Anderson, NMD

  • The Role of Immune Modulation in CancerAkbar Khan, MD

  • Turning Down the Volume on Fibromyalgia PainGinevra Liptan, MD

  • LDN and Neuroinflammation: How to Turn Down the FireSarah Zielsdorf, MD, MS

  • LDN: Its Use in Multiple Sclerosis and LupusPamela W. Smith, MD, MPH, MS

  • LDN and Dermatology: Psoriasis, Atopic DermatitisPamela W. Smith, MD, MPH, MS


Low-dose Naltrexone: The Promise