The Create Cures Foundation, has created two science and evidence-based Masterclasses about various dietary interventions, including fasting and its clinical applications, and that have been shown to have benefits for longevity and for the prevention of various diseases. The Masterclasses are based on Professor Valter Longo’s scientific research, as well as on the most relevant studies about longevity, nutrition, ageing, and other related diseases.

The course "Nutrition, Fasting, Longevity and Disease" and "Longevity Through Fasting and Nutrition" have been accredited by The Keck School of Medicine of USC and designed for 4 AMA PRA Category 1 Credits each.

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Nutrition, Fasting, Longevity and Disease

The course will explore in detail how fasting and nutrition influence longevity and contribute to the prevention of several diseases, as well as the use of diets to improve health. Nevertheless, there is yet no consensus around which diets are “safe”. Using science-based studies as its founding analytical instrument, this course will offer an up-to-date overview of the nutritional interventions, as well as their advantages and disadvantages regarding different types of diseases (cancer, diabetes, obesity, cardiovascular, autoimmune, and neurodegenerative diseases).

Upon completion of the course, the healthcare professionals will be able to re-evaluate, in their own practice and with individual patients, which of the learned approaches can be implemented to improve treatment and results.

The Keck School of Medicine of the University of Southern California designates this enduring activity for a maximum of 4 AMA PRA Category 1 Credits.


  • Identify dietary approaches to improve health
  • Allow the learner to discuss these approaches with their patients
  • Distinguish between dietary induced short- and long-term health benefits

Course Duration

  • The course duration is about 190 minutes
  • Quizzes and the finals exam require 40-60 minutes

CME Accreditation

The Keck School of Medicine of the University of Southern California designates this enduring activity for a maximum of 4 AMA PRA Category 1 Credits. Physicians should claim only the credits commensurate with the extent of their participation in the activity.

The Keck School of Medicine of USC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

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Content Modules

Module 1
Assessment of Biological Age and Disease Risk
Module 2
Nutrition, Fasting Mimicking Diets and Diabetes
Module 3
Nutrition, Fasting Mimicking Diets and Cancer
Module 4
Diets, Fasting and Cardiovascular Disease
Module 1
Nutrition and Longevity
Module 2
Fasting, Immunosenescence and Autoimmunity
Module 3
Genes, Fasting and Neurodegeneration
Module 4
Dietary Intervention, Health and Longevity

Bundle Includes

Longevity Through Fasting and Nutrition

The second masterclass is an in-depth follow-up of the first class. It will focus on the effects of nutrition and gene modulation by nutrients in relation to aging and lifespan. The course will also offer an introduction to the biology of ageing and to the mechanisms involved in longevity, as well as to those that can prevent age-related diseases. Starting from evidence-based data, the course will explore fasting and nutrition, clinical research, practical applications of fasting, and analyze specific clinical cases.

Upon course completion, physicians, biologists, pharmacists, nutritionists, and other healthcare professional will received both theoretical and practical information, as well as explore clinical cases about ageing, age-related diseases, nutrition, and the fast-mimicking diet.

The Keck School of Medicine of the University of Southern California designates this enduring activity for a maximum of 4 AMA PRA Category 1 Credits.


  1. Assess various fasting definitions and modalities
  2. Identify the benefits and risks of fasting based upon published scientific literature
  3. Integrate the knowledge of fasting, nutrition, and lifestyle in patient counseling

Course Duration

  • The course duration is about 220 minutes
  • Quizzes and the finals exam require 30-40 minutes

Content Modules

Module 1
Fasting, Nutrition, and Longevity
Module 2
The Science of Fasting Mimicking Diets
Module 3
Practical and Clinical Application
Module 4
Clinical Cases

Target Audience

  • Professionals in the healthcare sector (physicians, biologists, pharmacists, nutritionists) who will be able to request CME credits upon completion of an exam.
  • Enthusiasts of nutrition and healthy longevity, who will be able to receive a certificate upon completion of the course.

Certificates available after exam completion with CME Credits

Meet Your Instructors

Sebastian Brandhorst, PhD

Sebastian Brandhorst PhD, has scientific training based in cell biology, molecular biology, medicine, and biochemistry, all of which are highly relevant for his focus on biogerontology research to identify the mechanisms underlying cellular protection, as well as health- and lifespan-regulation, and their translation into clinical applications.

Dr. Brandhorst’s studies are focused on the role and application of short-term starvation, low calorie and/or low protein diets and fasting-mimicking diets on health and lifespan in pre-clinical to clinical studies.

Dr. Brandhorst is a Research Assistant Professor at the School of Gerontology at the University of Southern California (USC) in Los Angeles, California.

Roberta Buono, PhD

Background in biochemistry, cell biology, molecular biology, histology, flow cytometry analyses as well as a specific training in vivo study. She has conducted studies on the use of fasting-mimicking diet (FMD) and β-cell regeneration to reverse diabetes.

Romina Inés Cervigni, PhD

Romina Inés Cervigni, Nutritionist Biologist, obtained a PhD from the Open University (UK) focusing her attention on the cellular and molecular mechanisms of cancer cells, through basic biology research. She collaborated as a postdoctoral researcher in the field of neuroscience with the National Research Committee (CNR) in Naples and the Vita-Salute San Raffaele University in Milan, Italy.

Her professional career continued at the Polytechnic University of Marche, Italy, with a Master in Nutrition and Dietetics. this allowed her to combine the preparation and knowledge in different pathological areas with tools to optimize the healing potential of nutrition.

Together with the whole team at the Valter Longo Onlus Foundation, she helps patients suffering from a wide range of diseases to integrate food therapy with standard pharmacological treatments.

Osama Hamdy, MD, PhD

Osama Hamdy, MD, PhD is a world expert and recognized leader in obesity and nutrition in diabetes. Dr. Hamdy is a senior endocrinologist and Medical Director of the Joslin Obesity Clinical Program and Director of the Inpatient Diabetes Program at Joslin Diabetes Center.

He is also Associate Professor of Medicine at Harvard Medical School. He has a long and extensive clinical experience and is very active in nutrition and obesity clinical research.

His lab led to many innovations and discoveries that changed how we currently manage obesity in patients with either type 2 or type 1 diabetes.

Kurt Hong MD, PhD

Kurt Hong MD, PhD is dual board-certified in internal medicine and clinical nutrition. He is specialized in a comprehensive approach to managing patients with obesity, metabolic diseases, and other nutrition-related disorders.

Dr. Hong is committed to improving outcomes for patients through clinical and translational research. Current interests include study of macro and micro-nutrients affecting energy metabolism, impact of lifestyle intervention on healthcare utilization, nutrition support for aging, and innovative use of computational phenotyping and machine learning for management of chronic diseases.

Dr. Kurt Hong (MD, PhD, FACN) is Professor of Clinical Medicine and the Executive Director of Center for Clinical Nutrition and Applied Health Research at University of Southern California.

Morgan Levine, PhD

Ladder-rank Assistant Professor in the Department of Pathology at the Yale School of Medicine and a member of the Yale Combined Program in Computational Biology and Bioinformatics, and the Yale Center for Research on Aging.

Create Cures Foundation

Create Cures Foundation is a 501 (c)(3) nonprofit organization dedicated to the purpose of promoting creative, educational, and scientific programs aimed at ensuring healthy lives, improving the well-being of all ages, and reducing mortality due to noncommunicable diseases like cancer, diabetes, cardiovascular, autoimmune, and neurodegenerative disease, as well as obesity.

We want everyone, even patients without financial means, to be able to benefit from new knowledge and live a long and healthy life.

Create Cures Foundation will use only 25% of total earnings for operational costs and the remaining part of 75% will be invested in the Foundation’s social projects to offer children, teenagers, and younger and older adults the opportunity to live a long and healthy life, in particular for those who suffer from diseases and are in critical financial conditions, and to prevent and support the treatment of noncommunicable diseases like cancer, obesity, diabetes, cardiovascular, autoimmune, and neurodegenerative diseases.

In addition, the Create Cures Foundation provides scholarships for health practitioners unable to pay the full rate by offering the Multimedia Course for a free or reduced rate.

Our courses have been approved by:

The Keck School of Medicine of the University of Southern California

Course Bundle Longevity and Nutrition Masterclasses

Regular price: $598 – Bundle price: $549

Nutrition, Fasting, Longevity and Disease: $399

Longevity Through Fasting and Nutrition: $199


Course Bundle

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Nutrition, Fasting, Longevity and Disease

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Longevity Through Fasting and Nutrition

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The Create Cures Foundation’s multimedia Courses will operate primarily for educational purposes to teach practitioners or individuals about nutrition, health, and extending the human lifespan. The courses are qualified as an educational activity, as described by section 501(c)(3) of the IRS Code and developed not for the purpose of generating revenue. The teaching methods of the courses are objective, and the course content include the factual foundation of the treated scientific theory. The factual foundation is sufficiently detailed to allow students or users to form an independent conclusion about its effectiveness. The information here are provided for general knowledge with the sole purpose of improving or developing the students or users’ capabilities and are not a substitute of professional or medical advice or treatment for specific medical conditions. It is strongly recommended not to use this information to diagnose or treat a health problem or disease without consulting with a qualified primary care provider and/or specialist.


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