Module II: Neurovascular and Metabolic Synergy | December 12-14 in Las Vegas, NV

Unlock the power of interconnected systems to transform patient care.

Module II of A4M’s Fellowship in Longevity Medicine explores the complex synergy between the gut, brain, metabolic, and cardiovascular systems—offering a comprehensive framework for diagnosing, preventing, and treating chronic conditions at their root.

Key Topics Covered

Cardiovascular Health
Cardiovascular Health
  • Foundations of Heart Health: Identify the roles of diet, physical activity, and stress regulation in cardiovascular outcomes.
  • Risk Reduction: Learn to spot early warning signs and apply preventive strategies.
  • Integrative Approaches: Incorporate lifestyle and functional medicine into heart care.
Blood Sugar & Metabolic Health
Blood Sugar & Metabolic Health
  • Glucose & Insulin Dynamics: Understand the mechanisms of glucose metabolism and insulin sensitivity.
  • Lifestyle & Metabolism: Investigate how nutrition, exercise, and stress impact metabolic function.
  • Managing Metabolic Syndrome: Prevent and treat insulin resistance, Type 2 diabetes, and related conditions.
Gut Health & Immunity
Gut Health & Immunity
  • The Microbiome & Wellness: Examine how gut microbes influence immune response, inflammation, and chronic disease risk.
  • The Gut-Brain Axis: Explore the two-way communication between the GI tract and the brain—linking digestion to mood, memory, and cognition.
  • Gastrointestinal Disorders: Learn diagnostic strategies and therapeutic interventions for common GI issues.
Brain Health & Cognition
Brain Health & Cognition
  • Neurobiology of Function: Delve into the cellular and molecular foundations of cognition and emotional health.
  • Metabolism & the Mind: Discover the impact of blood sugar and nutrient delivery on brain function.
  • Cognitive Longevity: Gain tools for early detection, risk reduction, and enhancement of mental performance.

What You’ll Gain from This Module

  • Assess and manage cardiovascular risk using holistic protocols
  • Design comprehensive, multi-system care strategies for longevity-focused practice
  • Understand the principles of blood sugar regulation and its impact on chronic disease

About the Fellowship in Longevity Medicine

The A4M Fellowship in Longevity Medicine is the world’s premier training program for healthcare professionals committed to extending healthspan, preventing disease, and transforming the future of aging.
Grounded in the latest clinical research and real-world application, the Fellowship provides the knowledge, tools, and credentials to practice cutting-edge, personalized medicine.

Ready to advance your expertise?

Join thousands of practitioners worldwide who are redefining what it means to age well.

Register Now

Schedule

Friday, December 12, 2025

7:30 am
The GI Microbiome, Cardiovascular Disease and Hypertension with Cases
Todd LePine, MD
9:30 am
Break
10:00 am
Aging and Cardiovascular Disease with Cases
Mark Houston, MD, MS, MSc
11:30 am
TBD
12:00 pm
Lunch
1:30 pm
Pathophysiology, Diagnosis, Clinical Evaluation, Prevention and Integrative Management of Hypertension- Part 1
Mark Houston, MD, MS, MSc
3:00 pm
TBD
3:30 pm
Break
4:00 pm
Pathophysiology, Diagnosis, Clinical Evaluation, Prevention and Integrative Management of Hypertension- Part 2
Mark Houston, MD, MS, MSc
6:00 pm
Close of Session

Saturday, December 13, 2025

7:30 am
Hypertension Cases with Questions and Interactive Discussion
Mark Houston, MD, MS, MSc Todd LePine, MD
9:00 am
TBD
9:30 am
Break
10:00 am
Clinical Integrative Management of Dyslipidemia and Dyslipidemia- induced Cardiovascular Disease and Atherosclerosis
Mark Houston, MD, MS, MSc
12:00 pm
Lunch
1:30 pm
Clinical Integrative Management of Dyslipidemia and Dyslipidemia- induced Cardiovascular Disease and Atherosclerosis Part 2 with Cases and Interactive Discussion
Mark Houston, MD, MS, MSc
3:30 pm
Break
4:00 pm
Nutrition and Coronary Heart Disease
Deanna Minich, PhD
5:30 pm
Panel Discussion
Mark Houston, MD, MS, MSc Deanna Minich, PhD
6:00 pm
Close of Session

Sunday, December 14, 2025

7:30 am
Women and Heart Disease
Mimi Guarneri, MD
9:30 am
Break
10:00 am
Coronary Heart Disease, Myocardial Infarction, CHD Risk factors, Congestive Heart Failure. Cardiovascular Nutrition. Cardiovascular Genetics. Prevention and Treatment: An Integrative Approach using Personalized and Precision CV Medicine Part 1
Mark Houston, MD, MS, MSc
12:00 pm
Lunch
1:30 pm
Coronary Heart Disease, Myocardial Infarction, CHD Risk factors, Congestive Heart Failure. Cardiovascular Nutrition. Cardiovascular Genetics. Prevention and Treatment: An Integrative Approach using Personalized and Precision CV Medicine Part 2
Mark Houston, MD, MS, MSc
3:30 pm
Break
4:00 pm
Inflamed Brain and Broken Heart: The Brain-Heart Connection
David Perlmutter, MD
5:30 pm
Panel Discussion
Mark Houston, MD, MS, MSc David Perlmutter, MD Mimi Guarneri, MD
6:00 pm
Close of Session

Registration

Physician

$2750

Register Now

Allied
Health

$2250

Register Now

Hotel Information

The Venetian And Palazzo Resort
Resort Resort Resort Resort Resort Resort

The Venetian And Palazzo Resort

3355 S. Las Vegas Blvd. Las Vegas, NV 89109

Room Rate: $296/night (includes resort fee)
Expires: November 16, 2025 (limited availability)

Venetian | Group Code: RAMAN
Toll-free: (866) 659-9645
International: (702) 414-1100

Palazzo - (866) 659-9659

Venetian - Book Now

Cancellation Policy
A one night's deposit is due at the time of booking. The cancellation policy for your reservation is 30 DAYS prior to arrival. If the reservation is canceled within 30 days of arrival, your one-night deposit will be forfeited.