Florence Comite, MD

Florence Comite, MD is a clinician-scientist, endocrinologist, and the leading expert in the fields of healthy longevity and precision medicine. She is internationally known for her expertise in leveraging proprietary clinical and wearable data collected at her private clinical and virtual practice to detect, predict, and reverse biological aging, disorders of aging and optimize health and vitality.

A graduate of Yale School of Medicine, where she was a faculty member for twenty-five years with a triple appointment in Endocrinology (Internal Medicine and Pediatrics) and Reproductive Endocrinology (Gynecology and Andrology), Dr. Comite trained at the National Institutes of Health and founded Women’s Health at Yale, the nation’s first women-only clinic.

In 2005, Dr. Comite founded the Comite Center for Precision Medicine & Healthy Longevity in New York City, where she established a clinically proven, academic approach to personalized healthcare structured around the individualized clinical process known as Nof1™, where each patient is treated as a single subject clinical trial. In recent years, the Center has expanded to Palo Alto and Miami Beach.

Dr. Comite’s global clientele spans the population, from forward-thinking physicians to titans of industry and entrepreneurs. Every client benefits from the insights and interventions tailored to each person. Dr. Comite’s startup Groq Health scales her precise methodology of precision medicine to a digital clinic delivered virtually.

Dr. Comite has published original research and articles in numerous clinical journals, such as the New England Journal of Medicine, JAMA: The Journal of the American Medical Association, and the Journal of the Endocrine Society. She is known for her seminal research in children, women and men with the recognition of the fact that our entire system is critical in aging and disease. In 2013 she authored a bestselling book, Keep It Up: The Power of Precision Medicine to Conquer Low T and Revitalize Your Life, with a primary focus on androgen deficiency and vitality in aging men. Data from her clinical research and decades of clinical practice will be used to inform Dr. Comite’s next book, Invincible: Eliminate the Disorders of Aging for a Healthy, Long Life, which will be published by Little Brown, Spark in Spring 2026. She continues to captivate audiences around the world as a sought-after keynote speaker.