The ability to develop personalized treatment plans is dependent upon the ability to identify the molecular and phenotypic uniqueness of the individual patient. ‘Omics’ disciplines provide high precision tools that can form the underlying architecture of such tailored approaches. This course will explore clinical Genomics, Proteomics, and Metabolomics, with an emphasis on the application of these systems-biology disciplines. Specific topics will include:
- Isolating patterns of meaning within complex signals
- Clinical solutions
- Ability to interpret omics literature
- Ability to engage in omics-based clinical research.
Further topics include genomics, transcriptomics, proteomics, metabolomics, phenomics, bioinformatics, pattern recognition, metabolic network assessment, targeted vs. non-targeted analysis, laboratory methods, specimen selection, and specimen preparation. This course will also examine micronutrients as essential inputs, describing their effects on the genome, transcriptome, proteome, and metabolome. Instructors will assist participants in applying molecular network assessment and pattern recognition to patient care, in addition to using omics for therapeutic selection. Sessions will also identify biomarkers with functional vs. pathological implications, and the role of diet in shaping the genome, transcriptome, and metabolome. Lectures will also discuss the use of information technologies, mobile self-care tools, and mobile patient management tools—supporting the holistic development of the physician researcher by presenting a framework of clinical research skills.