Integrative Cancer Therapy Fellowship
Module III: Immunology of Cancer

Upon completion of the module, the participant will:

• Review current concepts in immunology
• Understand the function of T-lymphocytes, T-helper cells, T-suppressor cells, T-cytotoxic cells, B lymphocytes, monocytes, macrophages, natural killer cells, and lymphokine-activated killer cells
• Know the immunological tests that are currently available
• Review the medical literature on immunosuppression and cancer
• Look at the multifactorial basis of immunodeficiency in cancer patients
• Understand effector cell numbers and function
• Know immunoregulatory cells and immunomodulatory factors
• Look at immunosuppression and tumor cell burden
• Evaluate sold tumors in the light of immunological function
• Understand hematopoietic malignancies in the light of immunology
• Evaluate radiation-induced immunosuppression
• Comprehend chemotherapy-induced immunosuppression
• Look at the immune status of patients in clinical remission
• Lean treatments of caner-associated immunodeficiency
• Know biological response modifiers with immunorestorative properties
• Understand the chemical properties of thymic hormones
• Learn treatment of radiotherapy-induced immunosuppression
• Learn therapies for chemotherapy-induced immunosuppression
• Learn about cancer vaccines
• Understand the cytokine sources and their effects related to the growth and treatment of cancer
• Have a working knowledge of all of the interleukins
• Understand tumor necrosis factor alpha and its effects on inflammation, immune regulation, apoptosis, and endothelial damage
• Understand interferon therapy for specific cancers
• Understand the mode of action of interferons in cancer treatment
• Learn about monoclonal antibody therapy
• Study immunotoxins
• Learn new testing methods for immunological markers
• Train in granulocyte colony-stimulating factor therapies
• Understand the clinical implications of granulocyte-macrophage colony-stimulating factor therapies and immunomodulation
• Review heat shock proteins as regulators of the immune response
• Understand the role of gene rearrangement in the tumor response
• Look at how tumors avoid the immune response