Integrative Cancer Therapy Fellowship
Module II: The Biology of Cancer

Upon completion of the module, the participant will:

• Understand normal cell biology
• Explain apoptosis
• Comprehend cell differentiation and loss of cell differentiation
• Identify cell cycle deregulation including restriction point, pRb pathway, C-Myc proto-oncogene pathway
• Comprehend gene mutations and their role in oncogenesis
• Learn DNA repair mechanisms
• Learn cancers resulting from defects in repair pathways
• Understand that cancer cells grow best in an anaerobic environment
• Learn new strategies for underlying mechanisms of cancer
• Understanding the genetic basis of cancer
• Know the definition of cancer
• Understand the role that ionization and UV radiation places on carcinogenesis
• Look at viral carcinogenesis
• Review the literature on the epidemiology of cancer
• Look at mutations and cell defenses
• Know methods for cancer detection and biomarkers
• Know the growth characteristics of malignant cells
• Learn signal transduction mechanisms
• Study angiogenesis and is relationship in cancer development
• Understand the biology of tumor metastasis
• Review the molecular genetics of cancer