What is Regenerative Medicine?
Regenerative Medicine optimizes the body's endogenous mechanisms of self-repair and adds proven and near future exogenous treatments and technologies. Adult stem cells appear to be our most powerful tool at this time. Previous dogma concerning adult stem cells taught that neurons and myocytes did not have stem cells and the cells present at birth just declined in quantity and quality. It was also believed that hematopoietic stem cells in the bone marrow lacked plasticity and could not transform to other tissues. Current medical literature proves that adult stem cells exist in most tissues including brain, heart, muscles and liver. Hematopoietic stem cells (HSC) and endothelial progenitor cells (EPC) in the bone marrow have plasticity to potentially transform and repair all tissues and organs.
- In the hormone optimization component of Anti-Aging Medicine we are already optimizing stem cells. Progesterone via its metabolite allopregnenolone stimulates neural stem cells, testosterone stimulates muscle stem cells and EPC's which can improve erectile function, and growth hormone treatment for adult growth hormone deficiency improves the quantity and quality of EPC's. Estradiol improves incorporation and mobilization of EPC's.
- In the lifestyle component of Anti-Aging medicine we are optimizing our adult stem cells with exercise and control of glucose and insulin.
- In the neutraceutical component of Anti-Aging Medicine we are optimizing our adult stem cells with Resveratrol as we turn on genes such as SIR1 and with blueberry, green tea and vitamin D3. DHA in omega 3 fish oil promotes neurogenesis from neuronal stem cells.
A new phase of Regenerative Medicine has recently commenced with cryogenic preservation of adult stem cells in healthy patients for future use. These patients are the same pro-active population who follow Anti-Aging programs. After stimulation with granulocyte colony stimulating factor adult stem cells can be collected by aphaeresis and stored in separate aliquots for treatment of specific pathologies such as acute myocardial infarction or for overall immune system reconstitution. This paradigm shift is referred to as bio-insurance.